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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PGAM5
All Species:
30.3
Human Site:
S253
Identified Species:
55.56
UniProt:
Q96HS1
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96HS1
NP_612642.1
289
32004
S253
P
E
G
W
L
R
L
S
L
N
N
G
S
I
T
Chimpanzee
Pan troglodytes
XP_509498
465
51564
S253
P
E
G
W
L
R
L
S
L
N
N
G
S
I
T
Rhesus Macaque
Macaca mulatta
XP_001083353
235
26735
L200
E
G
W
L
R
L
S
L
N
N
G
S
I
T
H
Dog
Lupus familis
XP_543346
289
31978
S253
P
E
G
W
L
R
L
S
L
N
N
G
S
I
T
Cat
Felis silvestris
Mouse
Mus musculus
Q8BX10
288
31976
S252
P
E
G
W
L
R
L
S
L
N
N
G
S
I
T
Rat
Rattus norvegicus
Q562B5
288
32042
S252
P
E
G
W
L
R
L
S
L
N
N
G
S
I
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510978
229
26244
L194
E
G
W
L
R
M
S
L
N
N
G
S
I
T
H
Chicken
Gallus gallus
XP_415083
212
24106
L177
E
G
W
L
R
M
S
L
N
N
G
S
I
T
H
Frog
Xenopus laevis
Q5FWM4
275
30968
S239
P
E
A
W
L
R
I
S
L
N
N
G
S
I
T
Zebra Danio
Brachydanio rerio
Q502L2
289
32155
G253
P
E
G
W
L
R
L
G
L
N
N
G
S
I
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O46084
289
33147
N244
A
E
G
W
L
R
I
N
I
N
H
A
S
I
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q09422
284
32472
S248
P
E
G
W
L
R
M
S
L
G
N
C
S
L
T
Sea Urchin
Strong. purpuratus
XP_793164
286
31924
S250
P
E
A
W
L
R
M
S
L
Y
H
G
S
I
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
61.7
79.9
93
N.A.
93.4
92.7
N.A.
70.9
64.3
65
64.7
N.A.
46
N.A.
42.5
53.6
Protein Similarity:
100
62.1
81.3
97.5
N.A.
96.1
96.8
N.A.
76.8
70.5
78.1
77.1
N.A.
61.9
N.A.
59.1
67.1
P-Site Identity:
100
100
6.6
100
N.A.
100
100
N.A.
6.6
6.6
86.6
93.3
N.A.
60
N.A.
73.3
73.3
P-Site Similarity:
100
100
6.6
100
N.A.
100
100
N.A.
6.6
6.6
93.3
93.3
N.A.
86.6
N.A.
86.6
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
16
0
0
0
0
0
0
0
0
8
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
24
77
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
24
62
0
0
0
0
8
0
8
24
62
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
16
0
0
0
24
% H
% Ile:
0
0
0
0
0
0
16
0
8
0
0
0
24
70
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
24
77
8
47
24
70
0
0
0
0
8
0
% L
% Met:
0
0
0
0
0
16
16
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
8
24
85
62
0
0
0
0
% N
% Pro:
70
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
24
77
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
24
62
0
0
0
24
77
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
24
77
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
24
77
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _